300 New Genetic Variants Linked to Depression Discovered in Global Study

300 New Genetic Variants Linked to Depression Discovered in Global Study

it.euronews.com

300 New Genetic Variants Linked to Depression Discovered in Global Study

A study of five million people across 29 countries identified 300 new genetic variants linked to depression, highlighting the complex genetic basis of the disorder and paving the way for improved treatments.

Italian
United States
HealthScienceMental HealthResearchTreatmentGeneticsDepressionGenomics
University Of EdinburghKing's College LondonMayo ClinicBrain And Mind Centre (University Of Sydney)Queensland Institute Of Medical Research (Qimr Berghofer)
Cathryn LewisJacob CrouseBrittany Mitchell
What is the global significance of identifying 300 previously unknown genetic variants associated with depression?
A study of five million individuals identified 300 novel genetic variants linked to depression. Researchers from the University of Edinburgh and King's College London analyzed genetic data, uncovering 293 previously unknown variants associated with neurons in the amygdala and hippocampus.
How might the understanding of these newly discovered genetic variants impact the development of future treatments for depression?
This large-scale study, involving 680,000 individuals with depression and four million controls across 29 countries, revealed 697 genetic variants associated with the condition. The findings highlight the complex genetic basis of depression and its impact on brain regions.
What are the ethical considerations of using genetic risk scores to predict an individual's likelihood of developing depression, and how can these considerations be addressed in clinical practice?
The discovery of 308 genes increasing depression risk paves the way for improved treatments. However, the study emphasizes that depression's etiology is multifaceted, involving genetic, social, and psychological factors, cautioning against solely using genetic predisposition to predict individual outcomes.

Cognitive Concepts

2/5

Framing Bias

The framing emphasizes the significant genetic component of depression, highlighting the discovery of new gene variants. This focus, while factually accurate, might inadvertently downplay the importance of other contributing factors such as environment and social circumstances. The headline, if one existed, would likely reflect this emphasis on the genetic discoveries.

1/5

Language Bias

The language used is generally neutral and objective, reporting the findings of the study in a factual manner. However, phrases like "a great testament to the power of global cooperation" (in the quote from Dr. Crouse) could be considered slightly positive and subjective, but are not significantly loaded.

3/5

Bias by Omission

The article focuses heavily on the genetic aspects of depression, potentially overlooking the significant influence of environmental and social factors. While it mentions these factors briefly, a more in-depth exploration of their interaction with genetic predisposition would provide a more comprehensive understanding. The lack of discussion on socioeconomic disparities in access to mental healthcare could also be considered an omission.

2/5

False Dichotomy

The article doesn't explicitly present a false dichotomy, but the strong emphasis on genetic factors might inadvertently create an impression that genetics are the primary, or even sole, cause of depression, neglecting the complex interplay of biological, psychological, and social factors.