Colossal Biosciences Makes Headway in Dodo De-Extinction Project

Colossal Biosciences Makes Headway in Dodo De-Extinction Project

cnn.com

Colossal Biosciences Makes Headway in Dodo De-Extinction Project

Texas-based biotechnology firm Colossal Biosciences has successfully cultured primordial germ cells from rock doves, a crucial step towards their goal of creating a dodo bird, using gene-editing technology and surrogate chickens.

English
United States
TechnologyScienceGenetic EngineeringDe-ExtinctionColossal BiosciencesDodoAvian Conservation
Colossal BiosciencesWestern UniversityUniversity Of East Anglia
Beth ShapiroBen LammScott Macdougall-ShackletonCock Van OosterhoutAnna Keyte
What is the primary scientific breakthrough achieved by Colossal Biosciences, and what are its immediate implications?
Colossal Biosciences successfully cultured primordial germ cells from rock doves. This is a pivotal step in their dodo de-extinction project, as it enables the manipulation of avian reproductive cells for genetic modification. This technology also broadly advances avian reproductive technologies.
How does this advance in cell culturing contribute to the broader effort of 'de-extinction', and what are the subsequent steps?
The successful rock dove cell culture allows scientists to move forward with creating a dodo-like bird. The next step involves using these cells to create live rock pigeons via surrogate chickens (proof of concept). Afterwards, they will attempt to grow Nicobar pigeon germ cells (dodo's closest relative) and edit them with dodo traits before injecting them into genetically modified sterile chickens.
What are the major criticisms of Colossal's 'de-extinction' approach, and how does the company's work offer potential benefits beyond bringing back extinct species?
Critics argue that "de-extinction" is a misnomer, as it would create a genetically modified hybrid, not a true resurrected species. However, the developed technology offers valuable applications in avian conservation, particularly in enhancing genetic diversity of endangered species, helping them adapt to threats like habitat loss and diseases. It may allow for the introduction of resistant genes from historic samples or related species.

Cognitive Concepts

1/5

Framing Bias

The article presents a balanced view of Colossal's project, including both the excitement and controversy surrounding it, as well as critical perspectives from experts. The headline is descriptive rather than sensational.

1/5

Language Bias

The language used is largely neutral and objective, although terms like "pivotal step" and "resurrected" could be considered slightly loaded. The use of quotes from scientists adds objectivity. Alternatives could be 'significant step' and 'reconstructed'.

3/5

Bias by Omission

While the article covers various aspects, it could benefit from including more detailed information on the ethical considerations of de-extinction and the potential ecological impacts of introducing a genetically modified species. The long-term consequences and potential unintended effects are mentioned but not explored deeply.

Sustainable Development Goals

Life on Land Positive
Direct Relevance

Colossal Biosciences's project to "de-extinct" the dodo bird, while controversial, directly relates to Life on Land by exploring innovative genetic engineering techniques to potentially revive extinct species. The success in culturing primordial germ cells from pigeons is a significant step, demonstrating the potential for future applications in avian conservation and biodiversity restoration. The project also highlights the need for protecting existing species and ecosystems, furthering the understanding of biodiversity loss and its impact.