
dw.com
Lecanemab and the fight against Alzheimer's
New research sheds light on the cause of cell death in Alzheimer's disease, potentially opening new avenues for treatment, while the drug Lecanemab offers some hope in slowing progression.
Romanian
Germany
HealthResearchDementiaTreatmentMedicineAlzheimer's
FdaEmaUniversity College LondonNational Institute On AgingNih
Bart De Strooper
- What is Lecanemab and what is its current status?
- Lecanemab is a new drug that shows promise in slowing the progression of Alzheimer's disease, although it cannot cure it. It targets amyloid protein, a key factor in the disease's development.
- What were the initial and subsequent decisions by the EMA regarding Lecanemab?
- The European Medicines Agency (EMA) initially rejected lecanemab due to concerns about serious side effects, but later approved it for patients with a lower risk of such side effects.
- What are the potential implications of the new findings for Alzheimer's treatment?
- Researchers hope that understanding the link between abnormal proteins, MEG3, and necroptosis will lead to the development of new drugs that can effectively combat Alzheimer's disease by preventing neuronal death.
- How many people are affected by dementia globally, and what is the projected increase?
- Approximately 55 million people worldwide suffer from dementia, including Alzheimer's disease, and this number is projected to rise dramatically by 2050 due to an aging global population.
- What is the newly discovered connection between abnormal proteins and cell death in Alzheimer's?
- A new study suggests a direct link between abnormal amyloid and tau proteins, leading to necroptosis (a type of cell death) in Alzheimer's patients. Blocking the molecule MEG3, which is produced in this process, may help prevent neuron death.