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theguardian.com

Nurse's Death Linked to Weight-Loss Drug Mounjaro

A 58-year-old nurse died after taking the weight-loss drug Mounjaro, raising concerns about its safety and the UK government's plans for a large-scale trial.

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English

United Kingdom

HealthHealthcareDeathWeight LossDrug SafetyGovernment Trial

NhsUniversity Hospital MonklandsLillyMhra (Medicines And Healthcare Products Regulatory Agency)

Susan McgowanJade CampbellDr Alison Cave

What was the cause of death for Susan McGowan?: Susan McGowan, a 58-year-old nurse, died after receiving two low-dose injections of the weight-loss drug tirzepatide (Mounjaro). Her death certificate lists multiple organ failure, septic shock, and pancreatitis as the immediate cause, with tirzepatide use as a contributing factor.
What is the MHRA's stance on the safety of GLP-1 RAs?: The MHRA (Medicines and Healthcare products Regulatory Agency) stated that patient safety is their top priority and that the benefits of GLP-1 RAs (including Mounjaro) outweigh the risks for licensed indications. They maintain robust safety monitoring systems.
How much does Mounjaro cost, and where did McGowan obtain it?: The drug, Mounjaro, is approved for weight loss in the UK and costs \u00a3150-\u00a3200 for a four-week supply. McGowan purchased it through an online pharmacy after researching and seeking medical advice.
What symptoms did McGowan experience after her second injection?: Following her second injection, McGowan experienced severe stomach pains and sickness, leading her to seek emergency care at Monklands Hospital, where she later died despite her colleagues' efforts to save her.
What government trial involving tirzepatide is planned, and what concerns have been raised about it?: The UK government is planning a five-year trial in Greater Manchester, partnering with Lilly (Mounjaro's manufacturer), to provide tirzepatide to 3,000 unemployed individuals to aid their return to work; McGowan's niece expressed concerns about the timing of this trial.

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