telegraph.co.uk
Rapamycin and Lifespan Extension
Rapamycin, an immunosuppressant drug, shows promise in extending lifespan and improving healthspan but needs more research to confirm its effectiveness in humans.
English
United Kingdom
HealthScienceLifestyleResearchMedicineAnti-Aging
University Of Oxford
Philip BorgPeter AttiaBryan JohnsonLeslie KennyLarry Hayes
- What is the mTOR pathway and its role in rapamycin's effects?
- The mTOR pathway, a cellular signaling pathway involved in cell growth and metabolism, is targeted by rapamycin. By inhibiting this pathway, rapamycin may slow aging and treat various diseases.
- What is rapamycin and how does it potentially affect lifespan?
- Rapamycin, an immunosuppressant drug, shows promise in extending lifespan and improving healthspan by activating autophagy, a cellular self-cleaning process.
- What is the regulatory status of rapamycin's use for longevity?
- Rapamycin is currently licensed for transplant patients in the UK but is accessible online from other countries with less stringent regulations. Its use for longevity is not yet approved.
- What is the current evidence for rapamycin's effect on human lifespan?
- While research on rapamycin's lifespan-extending effects is promising in animal studies, human trials are needed to confirm its efficacy and safety for anti-aging purposes.
- How widespread is the off-label use of rapamycin for anti-aging purposes?
- Thousands are using rapamycin off-label for longevity, sharing experiences and side effects on social media and online forums, despite the lack of conclusive evidence supporting its use for lifespan extension.