Tag #De-Extinction

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repubblica.it

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Mar 5, 16:13

Gene-Edited Mice: A Step Towards Woolly Mammoth De-Extinction

Colossal Biosciences announced it successfully edited 7 genes in mice to give them a woolly mammoth-like coat and fat layer, a step towards their goal of de-extincting woolly mammoths using CRISPR technology and an artificial womb, raising ethical and ecological concerns.

Gene-Edited Mice: A Step Towards Woolly Mammoth De-Extinction

Colossal Biosciences announced it successfully edited 7 genes in mice to give them a woolly mammoth-like coat and fat layer, a step towards their goal of de-extincting woolly mammoths using CRISPR technology and an artificial womb, raising ethical and ecological concerns.

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What are the immediate implications of Colossal Biosciences' successful gene editing in mice, and what is its significance for the de-extinction of the woolly mammoth?

Colossal Biosciences, a US biotech firm, has successfully edited 7 genes in mice to produce a woolly coat and fat layer, a step towards recreating woolly mammoths. This involved modifying the mice's DNA to match that of mammoths, not inserting mammoth genes. The next steps involve creating an elephant-mammoth hybrid.

us.cnn.com

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Mar 4, 19:16

Woolly Mouse: A Step Towards Mammoth Resurrection

Colossal Biosciences created a woolly mouse with mammoth-like traits by modifying eight genes, aiming to validate its approach for resurrecting extinct animals; however, concerns remain about the applicability of this technique to elephants and the ethical implications.

Woolly Mouse: A Step Towards Mammoth Resurrection

Colossal Biosciences created a woolly mouse with mammoth-like traits by modifying eight genes, aiming to validate its approach for resurrecting extinct animals; however, concerns remain about the applicability of this technique to elephants and the ethical implications.

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What are the key genetic modifications made to create the woolly mouse, and how do they relate to mammoth adaptations?

The woolly mouse project validates Colossal's approach to resurrecting extinct traits by demonstrating the ability to simultaneously edit multiple genes and achieve the expected phenotypic changes. This success is a proof-of-principle for their larger goal of recreating extinct animals like the woolly mammoth.

forbes.com

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Jan 16, 10:09

Colossal Biosciences Secures \$200 Million in Funding, Valued at \$10.2 Billion

Colossal Biosciences, a company working to revive extinct species like the woolly mammoth, secured \$200 million in Series C funding, bringing its total funding to \$435 million and valuing the company at \$10.2 billion. The company plans to use the funds to advance genetic engineering technologies ...

Colossal Biosciences Secures \$200 Million in Funding, Valued at \$10.2 Billion

Colossal Biosciences, a company working to revive extinct species like the woolly mammoth, secured \$200 million in Series C funding, bringing its total funding to \$435 million and valuing the company at \$10.2 billion. The company plans to use the funds to advance genetic engineering technologies ...

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How does Colossal Biosciences's approach to de-extinction and species preservation integrate AI and genetic engineering technologies?

The funding round highlights significant investor confidence in Colossal's approach to genetic engineering and its potential impact on conservation efforts. The company's work with AI, computational biology, and genetic engineering extends beyond de-extinction to encompass broader species preservation.

nbcnews.com

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Mar 5, 04:08

Colossal Biosciences Genetically Engineers 'Woolly Mice,' Advancing 'De-Extinction' Technology

Colossal Biosciences successfully created mice with long, thick, woolly hair by simultaneously editing seven genes, showcasing a technological advance in precision gene-editing with potential applications in conservation and medicine, despite ethical concerns regarding its application to endangered ...

Colossal Biosciences Genetically Engineers 'Woolly Mice,' Advancing 'De-Extinction' Technology

Colossal Biosciences successfully created mice with long, thick, woolly hair by simultaneously editing seven genes, showcasing a technological advance in precision gene-editing with potential applications in conservation and medicine, despite ethical concerns regarding its application to endangered ...

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What are the potential broader implications of Colossal's technology beyond the 'de-extinction' efforts, and how might this research impact the fields of conservation and biomedicine in the future?

The successful gene editing in mice demonstrates the technological feasibility of creating animals with cold-tolerance traits similar to extinct species, potentially opening new avenues for conservation efforts and biomedicine. However, applying this technology to endangered Asian elephants presents ethical and logistical challenges. The commercialization of this technology through spin-off healthcare companies highlights the significant financial investment and potential for profit in this field.

cnn.com

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Mar 4, 16:11

Woolly Mammoth-Like Mouse Created, Advancing Colossal's Extinct Animal Resurrection Project

Colossal Biosciences successfully created a woolly mouse by genetically modifying seven genes, showcasing its gene-editing capabilities and advancing its plan to resurrect the woolly mammoth and other extinct animals, although concerns regarding the animal's cold-tolerance and the overall project's ...

Woolly Mammoth-Like Mouse Created, Advancing Colossal's Extinct Animal Resurrection Project

Colossal Biosciences successfully created a woolly mouse by genetically modifying seven genes, showcasing its gene-editing capabilities and advancing its plan to resurrect the woolly mammoth and other extinct animals, although concerns regarding the animal's cold-tolerance and the overall project's ...

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What are the main criticisms of the woolly mouse research, and what further steps are needed to validate Colossal's approach?

The woolly mouse project validates Colossal's approach to resurrecting extinct traits by demonstrating the successful modification of multiple genes simultaneously. This research, while not yet peer-reviewed, offers a proof-of-concept for transferring mammoth genes into another species, although concerns remain regarding the cold-tolerance of the modified mice.

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