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Huntington's Disease: CAG Repeat Expansion Identified as Key Disease Mechanism
New research shows that the Huntington's disease mutation, involving a repeated DNA sequence (CAG), expands over time, remaining harmless until it surpasses 150 repeats, triggering toxic protein production and neuronal death; this discovery could lead to new treatment strategies.
Huntington's Disease: CAG Repeat Expansion Identified as Key Disease Mechanism
New research shows that the Huntington's disease mutation, involving a repeated DNA sequence (CAG), expands over time, remaining harmless until it surpasses 150 repeats, triggering toxic protein production and neuronal death; this discovery could lead to new treatment strategies.
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