Tag #Epilepsy

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es.euronews.com

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Aug 24, 16:14

RTN Hyperactivity Drives Autism-Like Behaviors in Mice, Reversible by Epilepsy Drug

Stanford Medicine researchers discovered that hyperactivity in the reticular thalamic nucleus (RTN) of mice lacking the Cntnap2 gene drives autism-like behaviors, reversible by Z944, an experimental epilepsy drug, suggesting a shared pathophysiology and potential treatment.

RTN Hyperactivity Drives Autism-Like Behaviors in Mice, Reversible by Epilepsy Drug

Stanford Medicine researchers discovered that hyperactivity in the reticular thalamic nucleus (RTN) of mice lacking the Cntnap2 gene drives autism-like behaviors, reversible by Z944, an experimental epilepsy drug, suggesting a shared pathophysiology and potential treatment.

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What specific brain region's hyperactivity is linked to autism-like behaviors in mice, and what treatment reversed these behaviors?

Researchers at Stanford Medicine have identified that hyperactivity in the reticular thalamic nucleus (RTN), a brain region regulating sensory information flow, drives autism-like behaviors in mice lacking the Cntnap2 gene. Treatment with Z944, an experimental epilepsy drug, reversed multiple autism-related symptoms, including seizures, sensory sensitivity, and social deficits. This suggests a potential therapeutic target for autism.

dailymail.co.uk

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Jul 6, 04:11

Wimbledon School Crash: Driver Faces Charges Two Years After Fatal Accident

Two years after eight-year-old Nuria Sajjad and Selena Lau died when Claire Freemantle's Land Rover crashed into their school, new witnesses have prompted police to prepare a file for prosecutors to consider criminal charges, after an initial investigation was deemed flawed.

Wimbledon School Crash: Driver Faces Charges Two Years After Fatal Accident

Two years after eight-year-old Nuria Sajjad and Selena Lau died when Claire Freemantle's Land Rover crashed into their school, new witnesses have prompted police to prepare a file for prosecutors to consider criminal charges, after an initial investigation was deemed flawed.

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What prompted the reopening of the investigation into the Wimbledon school crash two years after the incident?

Two years after a Land Rover crashed into a school, killing two 8-year-old girls, the driver, Claire Freemantle, may face criminal charges. New witnesses have prompted a reopened investigation, focusing on inconsistencies with her initial claim of an epileptic seizure.

nos.nl

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Jun 3, 10:13

Seven Dead in Dutch Truck Accident; Driver on Trial

Seven people died and seven others were injured when a truck driven by Juan S., a 47-year-old Spaniard, careened off a dike during a barbecue in Nieuw-Beijerland, Netherlands, on August 27, 2022; S. is now on trial, with evidence suggesting a history of drug use and a possible epileptic seizure.

Seven Dead in Dutch Truck Accident; Driver on Trial

Seven people died and seven others were injured when a truck driven by Juan S., a 47-year-old Spaniard, careened off a dike during a barbecue in Nieuw-Beijerland, Netherlands, on August 27, 2022; S. is now on trial, with evidence suggesting a history of drug use and a possible epileptic seizure.

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What factors beyond the driver's actions may have contributed to the accident?

The accident highlights concerns about road safety in the Zuidzijde area of Nieuw-Beijerland, where the municipality had been discussing traffic improvements prior to the tragedy. The subsequent lowering of the speed limit to 30 km/h reflects these concerns. The driver's history of drug use and potential epilepsy further complicate the case.

pda.krsk.kp.ru

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Apr 29, 04:13

Krasnoyarsk Hospital Successfully Completes Second Awake Brain Surgery

Krasnoyarsk Regional Clinical Hospital neurosurgeons and anesthesiologists successfully completed a second awake brain surgery, a complex procedure previously limited to major federal clinics, on a 57-year-old woman with drug-resistant epilepsy; the hospital invested in new equipment and sent doctor...

Krasnoyarsk Hospital Successfully Completes Second Awake Brain Surgery

Krasnoyarsk Regional Clinical Hospital neurosurgeons and anesthesiologists successfully completed a second awake brain surgery, a complex procedure previously limited to major federal clinics, on a 57-year-old woman with drug-resistant epilepsy; the hospital invested in new equipment and sent doctor...

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What specific challenges were encountered during the second awake craniotomy, and how were they addressed?

Following training at federal centers like the Pirogov National Medical Surgical Center, the Krasnoyarsk team performed a second awake craniotomy. The second patient, a 57-year-old woman with drug-resistant epilepsy, presented unique challenges due to her weight, increasing the risk of respiratory complications. The successful surgery demonstrates the team's expertise and the hospital's investment in specialized equipment.

dailymail.co.uk

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Mar 27, 01:16

Former US Attorney Jessica Aber Dies Unexpectedly

Former US Attorney for the Eastern District of Virginia, Jessica Aber, 43, died unexpectedly at her Washington DC home on Saturday; her family revealed she suffered from epilepsy, a condition that can cause sudden death.

Former US Attorney Jessica Aber Dies Unexpectedly

Former US Attorney for the Eastern District of Virginia, Jessica Aber, 43, died unexpectedly at her Washington DC home on Saturday; her family revealed she suffered from epilepsy, a condition that can cause sudden death.

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What were Jessica Aber's most significant achievements and contributions during her tenure as US Attorney?

Aber's death highlights the risks associated with epilepsy. While sudden unexpected death in epilepsy (SUDEP) is rare, it's a known complication. Her case underscores the importance of awareness and management of this condition.

cbsnews.com

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Dec 21, 19:08

Successful Epilepsy Surgery After Misdiagnosis

Isaac Klapper, 18, underwent successful brain surgery on March 8, 2024, at the Cleveland Clinic to remove a cortical dysplasia causing epilepsy after years of misdiagnosis and medication failure, resolving his seizures and enabling him to focus on his future.

Successful Epilepsy Surgery After Misdiagnosis

Isaac Klapper, 18, underwent successful brain surgery on March 8, 2024, at the Cleveland Clinic to remove a cortical dysplasia causing epilepsy after years of misdiagnosis and medication failure, resolving his seizures and enabling him to focus on his future.

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What were the immediate consequences of Isaac Klapper's epilepsy, and how did the successful surgery impact his life?

Isaac Klapper, 18, suffered from daily episodes of head twitching and eye turning since age 10. Initially misdiagnosed with a movement disorder, he later received an epilepsy diagnosis at the Cleveland Clinic and underwent brain surgery to remove a "grape-sized abnormality" in his left cingulate gyrus. The surgery, performed on March 8, 2024, successfully eliminated his seizures.

elpais.com

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Jul 11, 01:15

Spanish Truck Driver Sentenced for Fatal Accident in Netherlands

A Spanish truck driver was sentenced to 38 months in prison for causing a fatal accident in the Netherlands in August 2022, killing six people, including a pregnant woman, due to an epileptic seizure while driving, highlighting failures in driver licensing processes.

Spanish Truck Driver Sentenced for Fatal Accident in Netherlands

A Spanish truck driver was sentenced to 38 months in prison for causing a fatal accident in the Netherlands in August 2022, killing six people, including a pregnant woman, due to an epileptic seizure while driving, highlighting failures in driver licensing processes.

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What were the immediate consequences of the truck driver's actions in Nieuw-Beijerland, Netherlands?

On August 27, 2022, a Spanish truck driver, Juan S., caused a fatal accident in Nieuw-Beijerland, Netherlands, killing six people, including an eight-month pregnant woman. He was sentenced to 38 months in prison and a five-year driving ban for causing the accident while experiencing an epileptic seizure.

telegraaf.nl

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Jun 11, 16:11

Truck Driver's Negligence Kills Seven in Netherlands

On August 27, 2023, in Nieuw-Beijerland, Netherlands, truck driver Juan S., disregarding medical advice and driving regulations due to epilepsy and cocaine use, caused an accident killing seven, including an unborn baby, and injuring many.

Truck Driver's Negligence Kills Seven in Netherlands

On August 27, 2023, in Nieuw-Beijerland, Netherlands, truck driver Juan S., disregarding medical advice and driving regulations due to epilepsy and cocaine use, caused an accident killing seven, including an unborn baby, and injuring many.

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How did Juan S.'s disregard for medical advice, including his use of cocaine and irregular medication intake, contribute to the accident?

Juan S.'s actions demonstrate a pattern of negligence and deception. He ignored medical advice concerning his epilepsy medication and cocaine use, which likely triggered the seizure that caused the accident. His subsequent attempts to regain his driving license show a lack of remorse for the victims and their families.

bbc.com

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Jun 1, 10:08

Bradford 10k Run Honors Daughter Lost to Rare Epilepsy

Cheryl Murphy from Pudsey is running the Bradford 10k on Sunday with friends and family to raise awareness and funds for hemiplegia Hemiconvulsion syndrome, a rare epilepsy that caused her two-year-old daughter Edie's death in 2015, after an event which the family believe could not have been predict...

Bradford 10k Run Honors Daughter Lost to Rare Epilepsy

Cheryl Murphy from Pudsey is running the Bradford 10k on Sunday with friends and family to raise awareness and funds for hemiplegia Hemiconvulsion syndrome, a rare epilepsy that caused her two-year-old daughter Edie's death in 2015, after an event which the family believe could not have been predict...

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How has running helped the Murphy family cope with grief and raise awareness of hemiplegia Hemiconvulsion syndrome?

This event marks a significant milestone in the Murphy family's fundraising, exceeding £35,000 since 2015. The family's running efforts, started as a way to cope with grief, has become a powerful symbol of Edie's memory and a method to raise awareness of this rare and often fatal epilepsy syndrome.

cbsnews.com

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Mar 27, 01:16

Massachusetts Teen's Invention Detects Epileptic Seizures

14-year-old Sarah Wang from Andover, Massachusetts, created Hand Band, a wearable device using a spring vibration sensor to detect and alert caregivers to epileptic seizures in real time via Bluetooth, addressing limitations of existing solutions.

Massachusetts Teen's Invention Detects Epileptic Seizures

14-year-old Sarah Wang from Andover, Massachusetts, created Hand Band, a wearable device using a spring vibration sensor to detect and alert caregivers to epileptic seizures in real time via Bluetooth, addressing limitations of existing solutions.

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What is the immediate impact of Sarah Wang's Hand Band invention on epilepsy care?

A 14-year-old girl, Sarah Wang, invented Hand Band, a wearable device detecting seizure-related hand movements to alert caregivers. This followed her grandmother's seizure, highlighting existing product limitations in cost, adjustability, and comfort. The device uses a spring vibration sensor to convert movements into electrical signals, triggering an alarm via Bluetooth.

news.sky.com

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Feb 20, 07:11

NHS Rolls Out New Drug for Rare Childhood Epilepsy

The NHS is providing fenfluramine, a new drug, to hundreds of children aged two and over in England with Lennox-Gastaut syndrome (LGS), a severe, rare form of epilepsy, to improve their quality of life by reducing seizures; it's the first non-cannabis-based treatment for LGS approved by NICE.

NHS Rolls Out New Drug for Rare Childhood Epilepsy

The NHS is providing fenfluramine, a new drug, to hundreds of children aged two and over in England with Lennox-Gastaut syndrome (LGS), a severe, rare form of epilepsy, to improve their quality of life by reducing seizures; it's the first non-cannabis-based treatment for LGS approved by NICE.

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How does fenfluramine's mechanism of action compare to previously available treatments for LGS?

Fenfluramine, the first non-cannabis-based treatment for LGS, addresses the unmet need for effective therapies beyond cannabidiol and clobazam. Its approval highlights the NHS's commitment to improving care for rare conditions. The drug's mechanism of action, increasing serotonin levels to reduce seizures, offers a novel therapeutic approach.

t24.com.tr

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Dec 5, 10:08

Epilepsy Stigma in Turkey Hinders Treatment, Increasing Mortality Risk

Professor İbrahim Öztura highlights the stigmatization of epilepsy in Turkey, emphasizing that delayed treatment due to this stigma can lead to severe seizures and death; approximately 75% of patients respond to medication, while the rest may need surgery; irregular sleep patterns increase the risk.

Epilepsy Stigma in Turkey Hinders Treatment, Increasing Mortality Risk

Professor İbrahim Öztura highlights the stigmatization of epilepsy in Turkey, emphasizing that delayed treatment due to this stigma can lead to severe seizures and death; approximately 75% of patients respond to medication, while the rest may need surgery; irregular sleep patterns increase the risk.

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How does irregular sleep impact epilepsy risk and severity?

The societal stigma surrounding epilepsy in Turkey hinders timely medical intervention. This delay in treatment increases the likelihood of major seizures and associated risks such as death by suffocation during nocturnal episodes. The misconception that epilepsy is a shameful condition prevents many patients from seeking necessary care, impacting their quality of life and overall health outcomes.

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