Tag #Genetic Variant

What is the significance of the discovery of a single genetic variation in understanding and treating type 1 diabetes in the Netherlands?

Dutch researchers have discovered a single genetic variation responsible for protecting against type 1 diabetes, affecting 100,000 people in the Netherlands. This discovery allows for more precise diagnosis and prediction of disease progression, paving the way for potential new treatments. The research, published in Cell, focuses on a variation in the insulin gene, present in 40% of the Dutch population, that prevents the immune system from attacking insulin-producing cells.