Tag #James Lind

What key aspects of Francis Hauksbee the Younger's 1743 trial proposal foreshadowed the modern clinical trial design, and what were the immediate implications of this innovative approach?

In 1743, Francis Hauksbee the Younger proposed a controlled trial design for venereal disease treatments, including his own, a decade before James Lind's famous scurvy trial. Hauksbee's 10-step plan involved 12 patients, comparing treatments and assessing long-term outcomes, a remarkably modern approach for its time. This innovative design, though never executed, likely influenced Lind's work.