Tag #Regenerative Medicine

Showing 13 to 22 of 22 results

theguardian.com

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Feb 20, 10:08

Acid Attack Victim's Sight Restored with Donated Placenta

Paul Laskey, a 43-year-old man, suffered severe eye damage from an acid attack in February 2023, but three amniotic tissue grafts from a donated placenta and upcoming stem cell treatment offer hope for vision restoration.

Acid Attack Victim's Sight Restored with Donated Placenta

Paul Laskey, a 43-year-old man, suffered severe eye damage from an acid attack in February 2023, but three amniotic tissue grafts from a donated placenta and upcoming stem cell treatment offer hope for vision restoration.

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What was the immediate impact of the acid attack on Paul Laskey, and how did donated placental tissue contribute to his subsequent treatment?

In February 2023, Paul Laskey suffered a corrosive acid attack that severely damaged his left eye, resulting in complete vision loss. After two emergency transplants and three amniotic tissue grafts from a donated placenta, his eye was saved, and he is now progressing to stem cell transplant treatments aimed at vision restoration.

theguardian.com

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Jan 29, 19:11

Implantable Heart Patches Show Promise in Treating Advanced Heart Failure

German researchers have created implantable heart patches from reprogrammed cells that successfully improved heart function in monkeys and a human patient with advanced heart failure, offering a less invasive alternative to transplants and artificial pumps.

Implantable Heart Patches Show Promise in Treating Advanced Heart Failure

German researchers have created implantable heart patches from reprogrammed cells that successfully improved heart function in monkeys and a human patient with advanced heart failure, offering a less invasive alternative to transplants and artificial pumps.

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What are the key advantages of using donor cells to create the heart patches, compared to using a patient's own cells, and what are the potential risks and limitations?

The patches, composed of heart muscle and connective tissue cells embedded in a collagen gel, are created from donor cells to bypass the time and cost constraints of using a patient's own cells. Successful implantation in a 46-year-old woman and rhesus macaques demonstrated improved heart function and no adverse effects like tumor formation or irregular heartbeat, unlike direct cell injection.

welt.de

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Jan 29, 19:11

Cardiac Patch Improves Heart Function in First Human Trial

A clinical trial in Germany shows that a cardiac patch containing 400 million heart cells improved a patient's heart function by 4% in three months, paving the way for a potential long-term treatment for heart failure.

Cardiac Patch Improves Heart Function in First Human Trial

A clinical trial in Germany shows that a cardiac patch containing 400 million heart cells improved a patient's heart function by 4% in three months, paving the way for a potential long-term treatment for heart failure.

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What are the immediate, measurable effects of the cardiac patch implant on heart function in the first human trial?

A new cardiac patch, containing 400 million heart cells, improved the left ventricle's pumping capacity from 35% to 39% in a 46-year-old woman with advanced heart failure over three months. The patch, tested successfully in rats and rhesus monkeys, is now being used in a clinical trial involving 15 patients, with plans to treat 53.

theglobeandmail.com

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Jan 28, 19:13

Genetically Engineered Mice with Two Male Parents Created

Chinese scientists genetically modified mouse embryonic stem cells to create bipaternal mice, achieving a low survival rate (12%) but opening possibilities for endangered species conservation and regenerative medicine.

Genetically Engineered Mice with Two Male Parents Created

Chinese scientists genetically modified mouse embryonic stem cells to create bipaternal mice, achieving a low survival rate (12%) but opening possibilities for endangered species conservation and regenerative medicine.

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Life on Land

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How does this research advance the understanding of genomic imprinting and its role in mammalian reproduction?

The study targeted imprinted genes, believed to prevent unisexual reproduction in mammals. By modifying 20 of these genes and using cloning, the scientists produced bipaternal mice, demonstrating the potential to bypass the need for female gametes. The success rate was low (12%), and offspring exhibited developmental defects, highlighting challenges in this technique.

pda.kp.ru

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Dec 11, 13:07

"New Collagen-Based Artificial Skin Shows Promise for Treating Burns and Chronic Wounds"

"Sechenov University scientists created a cost-effective collagen-based artificial skin incorporating lactoferrin to treat burns and chronic wounds; pig tests showed significant healing in three days, full recovery in 21 days; it will be initially used in veterinary medicine before human application...

"New Collagen-Based Artificial Skin Shows Promise for Treating Burns and Chronic Wounds"

"Sechenov University scientists created a cost-effective collagen-based artificial skin incorporating lactoferrin to treat burns and chronic wounds; pig tests showed significant healing in three days, full recovery in 21 days; it will be initially used in veterinary medicine before human application...

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"What is the key innovation of the new artificial skin developed at Sechenov University, and what are its immediate benefits compared to existing treatments?"

"A new collagen-based artificial skin developed at the Sechenov University in Russia shows promise for treating burns and chronic wounds. The biocompatible material, potentially incorporating lactoferrin, promotes faster healing and reduces infection risk by creating an optimal environment for tissue regeneration. Unlike other treatments, it is inexpensive and does not trigger immune responses."

elpais.com

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Jan 29, 22:11

Lab-Grown Heart Patch Shows Successful Human Heart Regeneration

A 46-year-old woman with severe heart failure received a lab-grown heart patch containing 800 million umbilical cord cells; post-transplant analysis confirmed successful heart regeneration, offering hope for millions with heart failure.

Lab-Grown Heart Patch Shows Successful Human Heart Regeneration

A 46-year-old woman with severe heart failure received a lab-grown heart patch containing 800 million umbilical cord cells; post-transplant analysis confirmed successful heart regeneration, offering hope for millions with heart failure.

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How does this experimental heart patch compare to other attempts at heart regeneration, and what are the limitations and challenges that still need to be addressed?

This research, published in Nature, demonstrates that lab-grown heart patches can integrate into human heart tissue, offering hope for the 99% of advanced heart failure patients ineligible for transplants. The patch, derived from umbilical cord cells, significantly improved one patient's cardiac output from 10% to 35%.

bbc.com

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Jan 29, 22:11

Lab-Grown Heart Patches Show Promise in Treating Advanced Heart Failure

German scientists report promising early results from a human trial of lab-grown heart muscle patches to treat advanced heart failure; a 46-year-old woman showed stable condition after receiving a patch before a heart transplant, offering hope for millions with limited treatment options.

Lab-Grown Heart Patches Show Promise in Treating Advanced Heart Failure

German scientists report promising early results from a human trial of lab-grown heart muscle patches to treat advanced heart failure; a 46-year-old woman showed stable condition after receiving a patch before a heart transplant, offering hope for millions with limited treatment options.

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What are the immediate implications of the successful human trial of lab-grown heart muscle patches for treating advanced heart failure?

Scientists in Germany have successfully tested lab-grown heart muscle patches in a small human trial, showing promise for treating advanced heart failure. One patient with severe heart failure received a patch and showed stable condition, with no adverse effects, before later receiving a heart transplant. The patches, grown from stem cells, are stitched onto the heart's surface to enhance pumping.

pda.kp.ru

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Jan 29, 04:10

Personalized Cell Products Show Promise in Regenerating Damaged Tissues

Sechenov University scientists are developing personalized biomedicinal cell products (BMCPs) for regenerating vocal cords, eardrums, and nasal cavities; these "cocktails" of a patient's cells and medication promote faster, scar-free healing, with initial success shown in eardrum regeneration in ani...

Personalized Cell Products Show Promise in Regenerating Damaged Tissues

Sechenov University scientists are developing personalized biomedicinal cell products (BMCPs) for regenerating vocal cords, eardrums, and nasal cavities; these "cocktails" of a patient's cells and medication promote faster, scar-free healing, with initial success shown in eardrum regeneration in ani...

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What are the potential long-term implications of BMCP technology, and what future applications are under development?

Future applications of BMCPs extend beyond the current focus on vocal cords, eardrums, and nasal cavities. Research is underway to create BMCPs for repairing defects in the urinary tract, suggesting a wide range of potential future medical applications.

repubblica.it

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Jan 20, 16:10

AI Model GPT-4b Boosts Stem Cell Reprogramming Efficiency 50-fold

OpenAI and Retro Biosciences' AI model, GPT-4b, shows 50 times increased efficiency in applying Yamanaka factors for stem cell reprogramming, potentially revolutionizing regenerative medicine and extending human lifespan, though ethical considerations and peer review are necessary.

AI Model GPT-4b Boosts Stem Cell Reprogramming Efficiency 50-fold

OpenAI and Retro Biosciences' AI model, GPT-4b, shows 50 times increased efficiency in applying Yamanaka factors for stem cell reprogramming, potentially revolutionizing regenerative medicine and extending human lifespan, though ethical considerations and peer review are necessary.

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What role did Sam Altman's investment play in the development of GPT-4b and Retro Biosciences' broader mission to extend human lifespan?

This AI-driven approach builds upon Shinya Yamanaka's 2006 discovery of induced pluripotent stem cells (iPS). GPT-4b addresses limitations of this technique, namely the risk of genetic errors. By optimizing the process, the model aims to accelerate regenerative medicine advancements and enhance longevity.

repubblica.it

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Dec 7, 01:07

Melbourne Researchers Develop 350x Faster 3D Bioprinter

Researchers at the University of Melbourne have developed a new 3D bioprinting technique using acoustic waves to position cells, increasing printing speed by up to 350 times and improving cell survival rates, potentially revolutionizing cancer research and drug development.

Melbourne Researchers Develop 350x Faster 3D Bioprinter

Researchers at the University of Melbourne have developed a new 3D bioprinting technique using acoustic waves to position cells, increasing printing speed by up to 350 times and improving cell survival rates, potentially revolutionizing cancer research and drug development.

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How does the dynamic interface printing method differ from traditional 3D bioprinting techniques, and what are the advantages of this new approach?

The new bioprinting technique offers substantial advancements over traditional methods by increasing speed by up to 350 times and improving cell survival rates. This enhanced precision in cell placement is crucial for creating functional tissues, as the correct arrangement of cells is essential for their survival and function. The technology's potential applications span various fields, including cancer research and drug development, leading to more effective therapies and potentially reducing animal testing.

Showing 13 to 22 of 22 results