Eli Lilly's Oral Semaglutide Shows Promise, Poised to Disrupt Weight-Loss Market
Eli Lilly's oral semaglutide, orforglipron, shows promising results with 14.7% average weight loss in phase two trials, prompting a $550 million revenue projection and expected launch next year, intensifying competition in the $25 billion global obesity drug market.
Eli Lilly's Oral Semaglutide Shows Promise, Poised to Disrupt Weight-Loss Market
Eli Lilly's oral semaglutide, orforglipron, shows promising results with 14.7% average weight loss in phase two trials, prompting a $550 million revenue projection and expected launch next year, intensifying competition in the $25 billion global obesity drug market.
Progress
48% Bias Score
Wegovy Approved for Heart Disease Treatment in Australia
Australia's TGA approved Wegovy (semaglutide) in December 2024 for treating cardiovascular disease in overweight and obese adults, reducing heart attack/stroke risk by 20% in a 17,604-person Select trial, but PBS listing remains undecided due to cost.
Wegovy Approved for Heart Disease Treatment in Australia
Australia's TGA approved Wegovy (semaglutide) in December 2024 for treating cardiovascular disease in overweight and obese adults, reducing heart attack/stroke risk by 20% in a 17,604-person Select trial, but PBS listing remains undecided due to cost.
Progress
36% Bias Score
UK Insurer Vitality Offers Discounted Weight Loss Medication
Vitality, the UK's third-largest health insurer, is offering its 1.9 million members discounts of up to 20% on anti-obesity medications like Wegovy and Mounjaro, based on BMI and health conditions, to combat the £6.5 billion annual cost of obesity to the NHS.
UK Insurer Vitality Offers Discounted Weight Loss Medication
Vitality, the UK's third-largest health insurer, is offering its 1.9 million members discounts of up to 20% on anti-obesity medications like Wegovy and Mounjaro, based on BMI and health conditions, to combat the £6.5 billion annual cost of obesity to the NHS.
Progress
40% Bias Score
Afghan Man Loses 125kg to Attend University
A 216kg Afghan man, Powerullah, lost 125kg in 10 months through a strict diet and intense exercise regime to attend university, overcoming health issues, social stigma, and mobility challenges.
Afghan Man Loses 125kg to Attend University
A 216kg Afghan man, Powerullah, lost 125kg in 10 months through a strict diet and intense exercise regime to attend university, overcoming health issues, social stigma, and mobility challenges.
Progress
36% Bias Score
GLP-1 RA Drugs Show Promise, but Limitations Remain
A study of 1.2 million medical records found that GLP-1 RA drugs, such as Ozempic and Wegovy, may reduce the risk of several health issues, including substance use disorders, psychiatric disorders, and dementia, by 8-18%, but also carry risks of nausea, vomiting, and pancreatic or kidney complicatio...
GLP-1 RA Drugs Show Promise, but Limitations Remain
A study of 1.2 million medical records found that GLP-1 RA drugs, such as Ozempic and Wegovy, may reduce the risk of several health issues, including substance use disorders, psychiatric disorders, and dementia, by 8-18%, but also carry risks of nausea, vomiting, and pancreatic or kidney complicatio...
Progress
44% Bias Score
GLP-1RA Drugs Show Potential Link to Reduced Risk of Mental Health and Cognitive Conditions
A study of over 1.2 million veterans' medical records suggests a possible link between GLP-1 receptor agonist drugs, such as Ozempic and Wegovy, and a reduced risk of various mental health conditions, including suicidal thoughts, schizophrenia, dementia, and Alzheimer's disease, although further res...
GLP-1RA Drugs Show Potential Link to Reduced Risk of Mental Health and Cognitive Conditions
A study of over 1.2 million veterans' medical records suggests a possible link between GLP-1 receptor agonist drugs, such as Ozempic and Wegovy, and a reduced risk of various mental health conditions, including suicidal thoughts, schizophrenia, dementia, and Alzheimer's disease, although further res...
Progress
44% Bias Score
Avoiding Glucose Spikes for Weight Loss: A Dietary Strategy
Avoiding rapid spikes in blood glucose, achieved by combining carbohydrates with fiber and protein, prevents excess sugar from being stored as fat, aiding weight loss and reducing long-term health risks like hypertension.
Avoiding Glucose Spikes for Weight Loss: A Dietary Strategy
Avoiding rapid spikes in blood glucose, achieved by combining carbohydrates with fiber and protein, prevents excess sugar from being stored as fat, aiding weight loss and reducing long-term health risks like hypertension.
Progress
44% Bias Score
GLP-1 Drugs: Reshaping Beauty Standards and Social Status
The increasing availability of GLP-1 weight-loss drugs is disrupting traditional beauty standards, potentially diminishing the status associated with thinness and prompting the affluent to seek new markers of distinction.
GLP-1 Drugs: Reshaping Beauty Standards and Social Status
The increasing availability of GLP-1 weight-loss drugs is disrupting traditional beauty standards, potentially diminishing the status associated with thinness and prompting the affluent to seek new markers of distinction.
Progress
52% Bias Score
Ozempic and Wegovy May Reduce Risk of Multiple Diseases: Large-Scale Study
A study of 1.2 million veterans' health records suggests that Ozempic and Wegovy, GLP-1 receptor agonists, may reduce risks of schizophrenia, Alzheimer's, and substance abuse, although further research is needed due to the study's limitations.
Ozempic and Wegovy May Reduce Risk of Multiple Diseases: Large-Scale Study
A study of 1.2 million veterans' health records suggests that Ozempic and Wegovy, GLP-1 receptor agonists, may reduce risks of schizophrenia, Alzheimer's, and substance abuse, although further research is needed due to the study's limitations.
Progress
52% Bias Score
Fat Cell Memory Explains Weight Regain After Dieting
A Nature study reveals that fat cells 'remember' being fat, making weight loss difficult; 90% of dieters regain weight due to epigenetic changes in fat cells that persist even after weight loss, highlighting the need for long-term lifestyle changes for sustainable weight management.
Fat Cell Memory Explains Weight Regain After Dieting
A Nature study reveals that fat cells 'remember' being fat, making weight loss difficult; 90% of dieters regain weight due to epigenetic changes in fat cells that persist even after weight loss, highlighting the need for long-term lifestyle changes for sustainable weight management.
Progress
40% Bias Score
Diabetes Drugs Linked to Reduced Risk of Mental Health Issues
A study of 1.2 million veterans' medical records found that the diabetes and weight-loss drugs Ozempic and Wegovy (GLP-1 receptor agonists) may be linked to a reduced risk of various mental health issues, including alcohol and substance use disorders, suicidal thoughts, schizophrenia, dementia, and ...
Diabetes Drugs Linked to Reduced Risk of Mental Health Issues
A study of 1.2 million veterans' medical records found that the diabetes and weight-loss drugs Ozempic and Wegovy (GLP-1 receptor agonists) may be linked to a reduced risk of various mental health issues, including alcohol and substance use disorders, suicidal thoughts, schizophrenia, dementia, and ...
Progress
24% Bias Score
Bariatric Surgery: A Last Resort for Severely Obese Children in the Netherlands
A scientific study in the Netherlands provides bariatric surgery to six obese children (13+) as a last resort after failed lifestyle interventions, addressing the rising rates of childhood obesity (12% overweight, 4.1% severely obese among 4-17 year olds) and its severe health consequences.
Bariatric Surgery: A Last Resort for Severely Obese Children in the Netherlands
A scientific study in the Netherlands provides bariatric surgery to six obese children (13+) as a last resort after failed lifestyle interventions, addressing the rising rates of childhood obesity (12% overweight, 4.1% severely obese among 4-17 year olds) and its severe health consequences.
Progress
48% Bias Score