Tag #Clinical Trials

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Psychedelic Retreat Shows Promise for PTSD Treatment, But Raises Concerns

Nine US military veterans with PTSD participated in a psychedelic retreat in Mexico using psilocybin and 5-MeO-DMT in March; eight reported significant symptom improvement, while one experienced negative effects; the Department of Veterans Affairs is conducting clinical trials to explore the potenti...

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welt.de
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mRNA Cancer Vaccines: Promising Trials, but No Approvals Yet

Despite initial hopes after the success of mRNA COVID-19 vaccines, no mRNA cancer vaccines have received approval yet; however, several are in clinical trials, showing potential for personalized cancer treatments but facing significant hurdles.

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cnn.com
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NIH Research Halted by Trump Administration's Communications Pause

The Trump administration's communications pause has blocked purchasing at the NIH, halting essential supplies for research and jeopardizing ongoing studies; researchers fear contract renewals will also be affected, creating further instability.

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repubblica.it
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CAR T-cell Therapy for Breast Cancer: Early Trials Show Promise, but Challenges Remain

Currently, 16 active phase I/II clinical trials are investigating CAR T-cell therapy for various solid tumors, including breast cancer, primarily in the US, focusing on safety and feasibility; results are preliminary, showing some encouraging but limited data, with no phase III trials yet.

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cnn.com
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18th-Century Trial Proposal Foreshadowed Modern Clinical Research

New research suggests Francis Hauksbee the Younger's 1743 proposal for a controlled clinical trial design, though never conducted, may have influenced James Lind's 1747 scurvy trial, marking a critical early step in the evolution of evidence-based medicine.

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npr.org
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NIH's $1.8 Billion Long COVID Investment: Slow Progress Fuels Patient Frustration

The NIH has invested $1.8 billion in long COVID research, yet millions of patients lack effective treatments, prompting calls for faster clinical trials and FDA approvals; research focuses on understanding the disease's mechanisms before large-scale trials.

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forbes.com
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OSE Immunotherapeutics Launches Global Phase 3 Trial for Cancer Vaccine

OSE Immunotherapeutics, a French biotech firm, launched a global Phase 3 trial for its cancer vaccine Tedopi, securing \$9.3 million in public funding and partnerships with AbbVie and Boehringer Ingelheim, resulting in a 66% stock increase over the past year.

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forbes.com
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NIH Clarifies Research Continuity Amidst Communications Pause

NIH Acting Director Matthew Memoli issued a memo clarifying that clinical trials and essential research can proceed despite a temporary communications pause ordered by President Trump, but new grant reviews and procurements for new studies are temporarily halted.

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dailymail.co.uk
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Modified Bird Virus Shows Promise in Treating Multiple Cancers

A Chinese study showed a modified bird virus, NDV-GT, shrunk or stopped tumor growth in 22 of 23 patients with eight different advanced cancers in a trial; further trials are planned.

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us.cnn.com
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18th Century Trial Proposal Foreshadowed Modern Clinical Research

Francis Hauksbee the Younger's 1743 proposal for a controlled trial design to test venereal disease treatments, predating James Lind's scurvy trial by a decade, reveals a surprisingly modern approach to medical research that was likely influential on Lind's work, though Hauksbee's proposal was never...

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edition.cnn.com
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18th-Century Trial Proposal Foreshadowed Modern Clinical Research

New research suggests Francis Hauksbee the Younger's 1743 proposal for a controlled clinical trial, though never conducted, may have influenced James Lind's 1747 scurvy trial, marking a pivotal moment in the evolution of modern clinical research.

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dw.com
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Groundbreaking Clinical Trials Anticipated in 2025

In 2025, several groundbreaking clinical trials will release preliminary data, including a large-scale US dietary study employing AI analysis (8,000+ adults), Oxford University's CBD trial for psychosis (1,000 patients), and research on personalized cancer vaccines.

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