Tag #Immunotherapy

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welt.de

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Jul 27, 07:11

Blood Markers Predict Success of Peanut Allergy Immunotherapy in Children

A Berlin-based study identified specific blood markers—lower immunoglobulins and cytokines—predicting the success of peanut allergy immunotherapy in 38 children, potentially enabling personalized treatment plans.

Blood Markers Predict Success of Peanut Allergy Immunotherapy in Children

A Berlin-based study identified specific blood markers—lower immunoglobulins and cytokines—predicting the success of peanut allergy immunotherapy in 38 children, potentially enabling personalized treatment plans.

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What specific blood markers indicate successful peanut allergy immunotherapy in children, and how could this improve treatment outcomes?

Researchers in Berlin have identified blood markers that predict the success of peanut allergy immunotherapy in children. A study of 38 children found that those with lower levels of immunoglobulins and cytokines before treatment responded better. This discovery could allow for personalized treatment plans based on individual immune profiles.

repubblica.it

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Jul 23, 19:11

Cancer Treatments and Sun Sensitivity: Precautions for Patients

Cancer patients on chemotherapy or radiotherapy, or using photosensitizing drugs like 5-fluorouracil or anti-EGFR medications, should strictly limit sun exposure due to increased risk of sunburn and skin toxicity; those on immunotherapy should follow general sun safety guidelines unless experiencing...

Cancer Treatments and Sun Sensitivity: Precautions for Patients

Cancer patients on chemotherapy or radiotherapy, or using photosensitizing drugs like 5-fluorouracil or anti-EGFR medications, should strictly limit sun exposure due to increased risk of sunburn and skin toxicity; those on immunotherapy should follow general sun safety guidelines unless experiencing...

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What specific cancer treatments significantly increase sun sensitivity, and what precautions should patients take?

Cancer patients, especially those undergoing chemotherapy or treatments increasing sun sensitivity, need extra sun safety precautions. Some chemotherapies, like 5-fluorouracil, anthracyclines, and methotrexate, increase UV sensitivity, causing easier sunburns. Patients with skin toxicity from medications like anti-EGFR drugs or those receiving radiotherapy should avoid sun exposure altogether.

dailymail.co.uk

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Jul 21, 07:11

Glioblastoma Patient Shows No Signs of Cancer After Immunotherapy Treatment

A 43-year-old man, Ben Trotman, diagnosed with glioblastoma in October 2022, is cancer-free following an experimental immunotherapy treatment at University College London Hospital, defying the typical 12-18 month survival rate for this aggressive brain cancer.

Glioblastoma Patient Shows No Signs of Cancer After Immunotherapy Treatment

A 43-year-old man, Ben Trotman, diagnosed with glioblastoma in October 2022, is cancer-free following an experimental immunotherapy treatment at University College London Hospital, defying the typical 12-18 month survival rate for this aggressive brain cancer.

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What is the significance of Ben Trotman's recovery from glioblastoma, and what immediate implications does it have for brain cancer treatment?

Ben Trotman, 43, diagnosed with glioblastoma in October 2022, is showing no signs of the disease after immunotherapy treatment. This is unusual given the typically 12-18 month survival rate for this aggressive brain cancer, especially since planned follow-up surgery to remove the tumor was not performed.

dailymail.co.uk

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Jul 18, 22:16

Universal Cancer Vaccine Shows Promise in Mice Studies

A new mRNA-based cancer vaccine, tested on mice with various cancers, demonstrates potential as a universal treatment, shrinking or eliminating tumors when combined with immunotherapy, improving survival rates significantly; however, human trials are still needed.

Universal Cancer Vaccine Shows Promise in Mice Studies

A new mRNA-based cancer vaccine, tested on mice with various cancers, demonstrates potential as a universal treatment, shrinking or eliminating tumors when combined with immunotherapy, improving survival rates significantly; however, human trials are still needed.

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What are the immediate implications of the successful testing of a universal cancer vaccine in mice, and what specific impact could it have on cancer treatment?

A new mRNA-based cancer vaccine, currently tested on mice, shows promising results in shrinking or eliminating tumors across various cancer types when combined with immunotherapy. The vaccine, unlike traditional approaches, doesn't target specific cancers but stimulates a broad immune response, leading to improved survival rates in treated mice.

elpais.com

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Jun 19, 22:15

mRNA-Based Immunotherapy Shows Promise, Potentially Lowering CAR-T Therapy Costs

A new mRNA-based immunotherapy treatment, developed by Carl June and colleagues at the University of Pennsylvania and Capstan, shows promise in treating autoimmune diseases and leukemia in preclinical trials, potentially lowering the cost to around €5,000 per dose.

mRNA-Based Immunotherapy Shows Promise, Potentially Lowering CAR-T Therapy Costs

A new mRNA-based immunotherapy treatment, developed by Carl June and colleagues at the University of Pennsylvania and Capstan, shows promise in treating autoimmune diseases and leukemia in preclinical trials, potentially lowering the cost to around €5,000 per dose.

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What are the immediate implications of this new mRNA-based CAR-T therapy, and how could it impact global healthcare access to cancer and autoimmune disease treatments?

A new immunotherapy treatment using lipid nanoparticles and messenger RNA (mRNA) has successfully treated leukemia in mice and rats, and autoimmune diseases in cell cultures. The treatment, developed by Carl June and colleagues, aims to significantly reduce the cost of CAR-T therapies, potentially making them accessible to more patients. This new approach may avoid permanent genetic changes, offering a safer alternative.

smh.com.au

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Jun 7, 13:14

Immunotherapy Shows Promise in Treating Cutaneous Squamous Cell Carcinoma

An Australian clinical trial demonstrates that a new immunotherapy using genetically modified antibodies significantly reduces recurrence of cutaneous squamous cell carcinoma (CSCC), offering a potential cure for this common, often deadly, cancer. The 24-month disease-free rate in the treatment arm ...

Immunotherapy Shows Promise in Treating Cutaneous Squamous Cell Carcinoma

An Australian clinical trial demonstrates that a new immunotherapy using genetically modified antibodies significantly reduces recurrence of cutaneous squamous cell carcinoma (CSCC), offering a potential cure for this common, often deadly, cancer. The 24-month disease-free rate in the treatment arm ...

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How did the failure of a previous CSCC treatment trial contribute to the development of this successful immunotherapy?

The success of this immunotherapy builds upon previous research into preventing CSCC recurrence. While an earlier trial with Carboplatin failed, it identified a high-risk patient subgroup, leading to the development of this targeted therapy. The new approach leverages the body's immune system to detect and eliminate microscopic cancer cells, addressing a key challenge in CSCC treatment.

english.elpais.com

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Jul 26, 16:11

CARINA Project: Revolutionizing Childhood Leukemia Treatment

Doctors Antonio Pérez and Persis Amrolia's CARINA Project, supported by Fight Kids Cancer, aims to improve CAR-T cell therapy for acute myeloid leukemia by developing universal cells from healthy donors, addressing cost and complexity issues, and potentially saving thousands of children's lives annu...

CARINA Project: Revolutionizing Childhood Leukemia Treatment

Doctors Antonio Pérez and Persis Amrolia's CARINA Project, supported by Fight Kids Cancer, aims to improve CAR-T cell therapy for acute myeloid leukemia by developing universal cells from healthy donors, addressing cost and complexity issues, and potentially saving thousands of children's lives annu...

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What are the key objectives and potential impact of the CARINA Project on childhood leukemia treatment?

Antonio Pérez and Persis Amrolia, leading researchers in childhood blood cancers, are collaborating on the CARINA Project, which aims to improve CAR-T cell therapy for acute myeloid leukemia. This new trial seeks to create universal cells from healthy donors, reducing costs and complexity while expanding treatment access. The project is supported by the Fight Kids Cancer initiative.

elpais.com

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Jul 21, 07:11

Universal CAR-T Cells for Acute Myeloid Leukemia: A Revolutionary Project

Antonio Pérez and Persis Amrolia, pediatric cancer specialists, launched the CARINA project, a revolutionary CAR-T cell therapy trial for acute myeloid leukemia, aiming to create cost-effective universal cells from healthy donors, supported by Fight Kids Cancer.

Universal CAR-T Cells for Acute Myeloid Leukemia: A Revolutionary Project

Antonio Pérez and Persis Amrolia, pediatric cancer specialists, launched the CARINA project, a revolutionary CAR-T cell therapy trial for acute myeloid leukemia, aiming to create cost-effective universal cells from healthy donors, supported by Fight Kids Cancer.

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What is the significance of the CARINA project in improving the treatment of acute myeloid leukemia?

Antonio Pérez and Persis Amrolia, leading pediatric cancer specialists, collaborated on a groundbreaking CAR-T cell therapy project, aiming to treat acute myeloid leukemia, a treatment-resistant cancer. Their project, supported by Fight Kids Cancer, seeks to create universal CAR-T cells from healthy donors, reducing costs and expanding access.

cbsnews.com

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Jul 19, 16:13

Metastatic Melanoma: Aggressive Treatment Yields Positive Results

Jennifer Frederick, 50, was diagnosed with metastatic malignant melanoma after discovering a lump in her groin; despite aggressive treatment causing severe side effects, scans show major improvement, highlighting advancements in immunotherapy and offering hope for long-term survival.

Metastatic Melanoma: Aggressive Treatment Yields Positive Results

Jennifer Frederick, 50, was diagnosed with metastatic malignant melanoma after discovering a lump in her groin; despite aggressive treatment causing severe side effects, scans show major improvement, highlighting advancements in immunotherapy and offering hope for long-term survival.

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What are the long-term implications of Frederick's treatment success, and what lessons can be learned regarding the future of melanoma treatment and patient care?

Frederick's experience underscores the evolving landscape of melanoma treatment. While her intensive treatment protocol was associated with significant side effects, the positive response suggests a potential for long-term remission, even in advanced stages. Her story highlights the critical role of early detection and intervention combined with innovative therapies in improving patient outcomes and long-term survival for individuals with metastatic melanoma.

welt.de

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Jul 9, 10:12

Cancer Research: Challenges and Advancements in Immunotherapy

A German podcast episode, "Aha! Ten Minutes of Everyday Knowledge," features Professor Stefan Fröhling discussing cancer research, highlighting challenges in rare cancers, the potential of immunotherapies (currently effective in 20% of patients), and the need for more personalized treatment strategi...

Cancer Research: Challenges and Advancements in Immunotherapy

A German podcast episode, "Aha! Ten Minutes of Everyday Knowledge," features Professor Stefan Fröhling discussing cancer research, highlighting challenges in rare cancers, the potential of immunotherapies (currently effective in 20% of patients), and the need for more personalized treatment strategi...

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What are the most significant challenges in cancer research, and how are these challenges impacting treatment effectiveness?

Aha! Ten Minutes of Everyday Knowledge" podcast episode discusses cancer research challenges and advancements. Professor Stefan Fröhling highlights research gaps in rare cancers due to limited prevalence hindering systematic studies, while emphasizing immunotherapy and cell therapy as promising treatments with current success rates capped at 20 percent. Late diagnoses and drug resistance remain significant obstacles.

elpais.com

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Jun 10, 16:12

Allergy Immunotherapy: Efficacy, Suitability, and Vaccine Types

Allergy immunotherapy, using repeated allergen doses, effectively reduces symptoms and improves quality of life for allergic rhinitis, asthma, and Hymenoptera venom anaphylaxis; injected vaccines show better patient compliance than sublingual ones.

Allergy Immunotherapy: Efficacy, Suitability, and Vaccine Types

Allergy immunotherapy, using repeated allergen doses, effectively reduces symptoms and improves quality of life for allergic rhinitis, asthma, and Hymenoptera venom anaphylaxis; injected vaccines show better patient compliance than sublingual ones.

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What are the key benefits and efficacy rates of allergy immunotherapy, particularly for Hymenoptera venom?

Allergy immunotherapy, or allergen vaccines, involve repeated doses of an allergen extract to restore immune balance and tolerance. Numerous studies show these vaccines reduce symptoms, medication use, and improve quality of life; early application may even prevent asthma. For Hymenoptera venom, effectiveness exceeds 95% for wasp and 90% for bee venom allergies.

theguardian.com

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Jun 6, 16:13

Cancer Treatment Breakthroughs Extend Patient Survival

Several breakthroughs in cancer treatment were announced, including new immunotherapies significantly increasing survival rates for head and neck, melanoma, and gastric cancers; Car T-cell therapy showing 40% longer survival in advanced gastric cancer; liquid biopsies enabling faster, personalized t...

Cancer Treatment Breakthroughs Extend Patient Survival

Several breakthroughs in cancer treatment were announced, including new immunotherapies significantly increasing survival rates for head and neck, melanoma, and gastric cancers; Car T-cell therapy showing 40% longer survival in advanced gastric cancer; liquid biopsies enabling faster, personalized t...

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What are the long-term implications of these breakthroughs for cancer care, and what future research directions are suggested by these findings?

The integration of AI could optimize the use of existing treatments like abiraterone for prostate cancer, eliminating disparities in access to life-extending therapies. Further research into these novel immunotherapies, combined with advancements in diagnostics like liquid biopsies and lifestyle interventions, suggests a paradigm shift in cancer treatment, improving both survival rates and quality of life for patients.

Showing 13 to 24 of 79 results