Tag #Mrna Vaccine

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cbsnews.com

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Feb 19, 19:15

mRNA Vaccine Shows Promise in Extending Survival for Early-Stage Pancreatic Cancer

A clinical trial at Memorial Sloan Kettering successfully used a customized mRNA vaccine alongside surgery and chemotherapy to treat early-stage pancreatic cancer, resulting in significantly extended survival time for eight of sixteen patients who showed strong immune responses and only two recurren...

mRNA Vaccine Shows Promise in Extending Survival for Early-Stage Pancreatic Cancer

A clinical trial at Memorial Sloan Kettering successfully used a customized mRNA vaccine alongside surgery and chemotherapy to treat early-stage pancreatic cancer, resulting in significantly extended survival time for eight of sixteen patients who showed strong immune responses and only two recurren...

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What are the immediate implications of the successful mRNA vaccine trial for early-stage pancreatic cancer patients?

A clinical trial at Memorial Sloan Kettering Cancer Center combined surgery, chemotherapy, and a customized mRNA vaccine for early-stage pancreatic cancer. Eight of sixteen patients showed strong immune responses, with only two experiencing cancer recurrence after 3.2 years. This contrasts with the typical recurrence within a year for similar patients treated with standard methods.

abcnews.go.com

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Jan 18, 04:06

Moderna Receives $590 Million for Accelerated Bird Flu Vaccine Development

The U.S. government awarded Moderna an additional $590 million to expedite development of an mRNA bird flu vaccine, bringing the total to $766 million, aiming to expand clinical trials for five subtypes and enhance pandemic preparedness amid 67 confirmed human cases since April 2024, with one death ...

Moderna Receives $590 Million for Accelerated Bird Flu Vaccine Development

The U.S. government awarded Moderna an additional $590 million to expedite development of an mRNA bird flu vaccine, bringing the total to $766 million, aiming to expand clinical trials for five subtypes and enhance pandemic preparedness amid 67 confirmed human cases since April 2024, with one death ...

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What is the immediate impact of the $590 million investment in Moderna's bird flu vaccine development?

The U.S. government awarded Moderna $590 million to accelerate development of an mRNA-based bird flu vaccine, adding to a previous $176 million investment. This funding will expedite clinical trials for five additional influenza subtypes, bolstering the nation's pandemic preparedness.

pda.kp.ru

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Dec 1, 19:16

Gamaleya Institute's mRNA Cancer Vaccine Shows Promise in Preclinical Trials

Preclinical trials of Gamaleya Research Institute's mRNA melanoma vaccine show tumor and metastasis regression in animals; human trials are planned for autumn 2025, initially combining the vaccine with other therapies for advanced cancers; future development aims for personalized, affordable vaccine...

Gamaleya Institute's mRNA Cancer Vaccine Shows Promise in Preclinical Trials

Preclinical trials of Gamaleya Research Institute's mRNA melanoma vaccine show tumor and metastasis regression in animals; human trials are planned for autumn 2025, initially combining the vaccine with other therapies for advanced cancers; future development aims for personalized, affordable vaccine...

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How will the vaccine be used in clinical trials, and what are the plans for future research directions?

The Gamaleya Institute is developing a personalized mRNA vaccine against melanoma that targets both the primary tumor and metastases. Successful preclinical results indicate potential for treating various cancers, including lung, kidney, and brain cancers, although further research is needed.

nbcnews.com

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Feb 19, 19:15

Personalized mRNA Vaccines Show Promise in Pancreatic Cancer Treatment

A phase 1 clinical trial shows personalized mRNA vaccines generated a durable T-cell response in 50% of 16 patients with operable pancreatic cancer, lasting nearly eight years post-surgery, offering a potential new treatment for this deadly disease.

Personalized mRNA Vaccines Show Promise in Pancreatic Cancer Treatment

A phase 1 clinical trial shows personalized mRNA vaccines generated a durable T-cell response in 50% of 16 patients with operable pancreatic cancer, lasting nearly eight years post-surgery, offering a potential new treatment for this deadly disease.

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How does this trial challenge previous assumptions about the suitability of mRNA vaccines for treating pancreatic cancer, and what are the underlying reasons for this success?

This study challenges the assumption that pancreatic cancer's limited mutational targets hinder mRNA vaccine efficacy. The success in generating durable T-cell responses in half of the participants, despite the disease's aggressive spread, suggests a potential new approach to treating this deadly cancer. The vaccine's ability to target unique tumor mutations and the longevity of the T-cell response are key advancements.

bari.repubblica.it

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Dec 9, 19:09

World-First Personalized mRNA Cancer Vaccine Shows Promise in Treating Urinary Tract Cancer

A 75-year-old woman at Bari's Policlinico hospital became the first globally to receive a personalized mRNA cancer vaccine (cevumeran) alongside nivolumab immunotherapy after surgery for high-risk urinary tract cancer; this innovative treatment is designed to address specific tumor mutations, offeri...

World-First Personalized mRNA Cancer Vaccine Shows Promise in Treating Urinary Tract Cancer

A 75-year-old woman at Bari's Policlinico hospital became the first globally to receive a personalized mRNA cancer vaccine (cevumeran) alongside nivolumab immunotherapy after surgery for high-risk urinary tract cancer; this innovative treatment is designed to address specific tumor mutations, offeri...

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What is the significance of this world-first treatment for urinary tract cancer at Bari's Policlinico?

At Bari's Policlinico hospital, a 75-year-old woman with high-risk urinary tract cancer received a world-first treatment: a personalized mRNA vaccine (cevumeran) combined with nivolumab immunotherapy following surgery. The mRNA vaccine targets specific tumor mutations, boosting the immune system's attack on cancer cells. This innovative approach offers hope beyond conventional chemotherapy, which has limited efficacy and high toxicity.

Showing 13 to 17 of 17 results