Tag #Side Effects

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lemonde.fr

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Aug 25, 13:20

FDA Suspends Chikungunya Vaccine Ixchiq Due to Severe Side Effects

The U.S. FDA suspended the chikungunya vaccine Ixchiq due to new reports of severe side effects in four patients aged 55-82, halting U.S. sales and distribution; this follows previous suspensions in France and the EU, raising concerns about its future.

FDA Suspends Chikungunya Vaccine Ixchiq Due to Severe Side Effects

The U.S. FDA suspended the chikungunya vaccine Ixchiq due to new reports of severe side effects in four patients aged 55-82, halting U.S. sales and distribution; this follows previous suspensions in France and the EU, raising concerns about its future.

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What is the immediate impact of the FDA's suspension of the Ixchiq chikungunya vaccine on its distribution and the vaccine developer, Valneva?

The U.S. Food and Drug Administration (FDA) has suspended the authorization of Ixchiq, a chikungunya vaccine, due to new reports of severe side effects, including four cases in patients aged 55-82. This suspension immediately halts sales and distribution in the U.S., significantly impacting Valneva, the vaccine's developer.

dailymail.co.uk

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Aug 11, 22:16

Prednisone's Link to Depression and Mood Swings in Millions of Americans

Annual prednisone prescriptions in the US number 18 million; however, long-term use of this corticosteroid can cause severe depression, anxiety, and mood swings due to its impact on the brain's stress response and hormone regulation.

Prednisone's Link to Depression and Mood Swings in Millions of Americans

Annual prednisone prescriptions in the US number 18 million; however, long-term use of this corticosteroid can cause severe depression, anxiety, and mood swings due to its impact on the brain's stress response and hormone regulation.

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How does prednisone's mechanism of action contribute to its impact on mood and mental health?

Long-term prednisone use mimics the effects of cortisol, leading to a depletion of natural mood-boosting hormones and HPA axis dysregulation. This can manifest as depression, anxiety, mania, or psychosis, particularly at high doses (over 40mg daily). Women and older patients may be more susceptible due to increased hormone fluctuation and medication sensitivity.

mk.ru

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Jun 7, 13:13

Coffee's Harmful Interaction with Common Medications

A pharmacist warns that coffee consumption can negatively interact with numerous medications, including thyroid drugs, antidepressants, ADHD medications, and cold remedies, potentially reducing their effectiveness or increasing side effects like irregular heartbeat, insomnia, and headaches.

Coffee's Harmful Interaction with Common Medications

A pharmacist warns that coffee consumption can negatively interact with numerous medications, including thyroid drugs, antidepressants, ADHD medications, and cold remedies, potentially reducing their effectiveness or increasing side effects like irregular heartbeat, insomnia, and headaches.

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How does caffeine's interaction vary between different types of medications?

Coffee's interaction with medications stems from caffeine's stimulating properties. This can either accelerate drug absorption, potentially increasing side effects, or compete with the liver's processing of certain drugs, reducing effectiveness. For instance, consuming coffee with thyroid medication can decrease its absorption by up to 50%.

dailymail.co.uk

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May 4, 01:12

UK: Thousands of Elderly Patients Face Risks from Long-Term Antidepressant Use

In the UK, over 20 percent of people over 65 take antidepressants—double the amount from 20 years ago—leading to increased risks of falls and memory problems; experts criticize GPs for insufficient alternative treatments and oversight, while GPs cite long NHS waiting lists for talking therapies as a...

UK: Thousands of Elderly Patients Face Risks from Long-Term Antidepressant Use

In the UK, over 20 percent of people over 65 take antidepressants—double the amount from 20 years ago—leading to increased risks of falls and memory problems; experts criticize GPs for insufficient alternative treatments and oversight, while GPs cite long NHS waiting lists for talking therapies as a...

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Why are older patients remaining on antidepressants for extended periods, and what role do GPs and the NHS play in this situation?

The rising number of older adults on long-term antidepressants is linked to several factors: inadequate access to alternative treatments such as talking therapies (less than 6 percent of referrals are over 65), long NHS waiting lists for alternative care, and a lack of GP oversight leading to indefinite prescriptions. The absence of clear NHS guidelines on duration of antidepressant use further complicates the issue.

dailymail.co.uk

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Apr 24, 01:16

FDA Warns of Serious Side Effects from Online Topical Finasteride

The FDA warned about serious side effects, including sexual dysfunction and suicidal ideation, from unapproved topical finasteride hair-loss treatments sold online by telehealth companies like Hims, Hers, and Ro, with 32 complaints filed between 2019 and 2024.

FDA Warns of Serious Side Effects from Online Topical Finasteride

The FDA warned about serious side effects, including sexual dysfunction and suicidal ideation, from unapproved topical finasteride hair-loss treatments sold online by telehealth companies like Hims, Hers, and Ro, with 32 complaints filed between 2019 and 2024.

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What are the immediate health risks and regulatory concerns surrounding the online sale of unapproved topical finasteride products?

The FDA issued a warning about serious side effects from topical finasteride, an unapproved hair-loss drug sold online by companies like Hims, Hers, and Ro. Thirty-two complaints were filed between 2019 and 2024, detailing issues like erectile dysfunction, depression, and suicidal thoughts; some effects persisted after stopping use. The FDA also highlights the risk of fetal abnormalities in pregnant women.

dw.com

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Jan 28, 22:12

GLP-1 RA Drugs Show Promise, but Limitations Remain

A study of 1.2 million medical records found that GLP-1 RA drugs, such as Ozempic and Wegovy, may reduce the risk of several health issues, including substance use disorders, psychiatric disorders, and dementia, by 8-18%, but also carry risks of nausea, vomiting, and pancreatic or kidney complicatio...

GLP-1 RA Drugs Show Promise, but Limitations Remain

A study of 1.2 million medical records found that GLP-1 RA drugs, such as Ozempic and Wegovy, may reduce the risk of several health issues, including substance use disorders, psychiatric disorders, and dementia, by 8-18%, but also carry risks of nausea, vomiting, and pancreatic or kidney complicatio...

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What are the broader systemic implications of this study's findings considering its limitations in sample representation and study design?

The study focused on GLP-1 receptor agonists (GLP-1 RAs), a class of drugs that includes Ozempic and Wegovy. These drugs affect brain receptors involved in impulse control, reward, and addiction, potentially explaining their impact on appetite and addiction disorders. The observed benefits were linked to the drugs' ability to reduce blood glucose levels and slow intestinal emptying.

forbes.com

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Aug 20, 01:20

Ozempic Mouth: A New Beauty Concern Emerges from Weight-Loss Drugs

The increasing use of weight-loss drugs like Ozempic is causing a new cosmetic concern dubbed "Ozempic mouth," characterized by changes in facial structure leading to an aged or sunken smile appearance due to fat loss in the cheeks and jawline, alongside various oral health issues like dry mouth and...

Ozempic Mouth: A New Beauty Concern Emerges from Weight-Loss Drugs

The increasing use of weight-loss drugs like Ozempic is causing a new cosmetic concern dubbed "Ozempic mouth," characterized by changes in facial structure leading to an aged or sunken smile appearance due to fat loss in the cheeks and jawline, alongside various oral health issues like dry mouth and...

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What are the immediate and specific impacts of GLP-1 weight-loss drugs, such as Ozempic, on facial aesthetics and oral health?

The increasing use of GLP-1 weight-loss drugs like Ozempic has led to a noticeable side effect: "Ozempic mouth." This involves changes in facial structure due to fat loss in the cheeks and jawline, resulting in more prominent gums and an aged or sunken appearance. Many users, while achieving their desired weight, experience a simultaneous decrease in smile aesthetics.

cbsnews.com

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Jul 2, 10:12

Essure Birth Control Device Faces 27,000 Complaints, FDA Scrutiny

The Essure permanent birth control device, despite FDA approval, has prompted nearly 27,000 complaints since 2002 due to reported severe side effects like pain and organ perforation, leading to sales restrictions, a black box warning, and a mandated FDA post-market trial concluding in 2023.

Essure Birth Control Device Faces 27,000 Complaints, FDA Scrutiny

The Essure permanent birth control device, despite FDA approval, has prompted nearly 27,000 complaints since 2002 due to reported severe side effects like pain and organ perforation, leading to sales restrictions, a black box warning, and a mandated FDA post-market trial concluding in 2023.

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What are the immediate health consequences and systemic impacts stemming from the reported side effects of Essure, and how has the FDA responded?

Tens of thousands of women have reported severe side effects from Essure, a permanent birth control device, including pain, allergic reactions, and organ perforation. The FDA has received nearly 27,000 complaints since 2002, leading to sales restrictions and a black box warning. Women report significant impacts on their lives, some undergoing hysterectomies.

tr.euronews.com

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Jun 7, 22:10

Mindfulness Meditation: Potential for Serious Negative Side Effects

Studies reveal that over 10% of regular meditators in the US experienced negative effects lasting at least one month, including anxiety, depression, and psychotic symptoms, raising ethical concerns about the industry's promotion and clinical application due to limited scientific knowledge on safe pr...

Mindfulness Meditation: Potential for Serious Negative Side Effects

Studies reveal that over 10% of regular meditators in the US experienced negative effects lasting at least one month, including anxiety, depression, and psychotic symptoms, raising ethical concerns about the industry's promotion and clinical application due to limited scientific knowledge on safe pr...

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What ethical concerns arise from the commercialization and clinical application of mindfulness and meditation practices given the potential for adverse effects?

While mindfulness and meditation boast proven benefits, research increasingly highlights potential adverse effects such as anxiety, depression, and psychotic symptoms. A 2022 study involving over 8,000 UK schoolchildren aged 11-14 found no significant improvement in mental health from mindfulness training; in some cases, it was even deemed harmful. This underscores the need for caution and further research.

mk.ru

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Apr 30, 10:11

Exercise Shown to Significantly Reduce Cancer Treatment Side Effects

A large-scale review of 80 studies, published in the British Journal of Sports Medicine, found that physical exercise significantly reduces cancer treatment side effects, improving patients' quality of life and long-term health.

Exercise Shown to Significantly Reduce Cancer Treatment Side Effects

A large-scale review of 80 studies, published in the British Journal of Sports Medicine, found that physical exercise significantly reduces cancer treatment side effects, improving patients' quality of life and long-term health.

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What are the key findings of the most comprehensive review to date on the impact of exercise on cancer patients' health outcomes?

A comprehensive review published in the British Journal of Sports Medicine reveals that exercise significantly reduces cancer treatment side effects. The study, involving 485 reviews from 80 articles, showed exercise mitigated chemotherapy-related cardiotoxicity, neuropathy, and cognitive impairment (brain fog). Improvements in sleep quality, psychological well-being, and overall quality of life were also observed.

dw.com

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Feb 17, 13:10

UV Light Irradiation Improves Cancer Immunotherapy Tolerability

A Freiburg University study shows UV light irradiation of immune cells significantly improves immunotherapy tolerability in cancer patients by reducing side effects like colitis, hepatitis, and dermatitis without hindering anti-tumor activity, impacting 14 patients across three German university hos...

UV Light Irradiation Improves Cancer Immunotherapy Tolerability

A Freiburg University study shows UV light irradiation of immune cells significantly improves immunotherapy tolerability in cancer patients by reducing side effects like colitis, hepatitis, and dermatitis without hindering anti-tumor activity, impacting 14 patients across three German university hos...

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What is the immediate impact of UV light irradiation on the tolerability of cancer immunotherapy?

A Freiburg University study found that UV light irradiation of immune cells significantly improves the tolerability of immunotherapy in cancer patients, reducing side effects like colitis, hepatitis, and dermatitis without compromising anti-tumor activity. In a small trial (14 patients), all participants with colitis were cured, and 92% reported significantly reduced inflammation symptoms after treatment.

bbc.com

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Jan 24, 19:09

Finasteride's Dark Side: Online Access and Severe Side Effects

A 26-year-old British man, Kyle, suffered severe side effects, including suicidal thoughts and sexual dysfunction, after using finasteride obtained easily online last spring; this prompted the UK to mandate stronger warnings on the drug's packaging.

Finasteride's Dark Side: Online Access and Severe Side Effects

A 26-year-old British man, Kyle, suffered severe side effects, including suicidal thoughts and sexual dysfunction, after using finasteride obtained easily online last spring; this prompted the UK to mandate stronger warnings on the drug's packaging.

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How did the ease of access to finasteride online, including obtaining a prescription with minimal checks, contribute to Kyle's negative experience?

Finasteride, while effective for many, carries significant risks such as depression and sexual dysfunction. Kyle's case highlights the dangers of readily available online prescriptions without thorough medical assessment. The UK's regulatory response, mandating stronger warnings, reflects growing concern over these side effects.

Showing 1 to 12 of 21 results