Tag #Stem Cells

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elpais.com

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Sep 12, 10:19

Stem Cell Therapy: Current Status and Future Prospects

Despite theoretical potential, stem cell applications in tissue repair remain largely in research, with only three treatments—chondrocyte, corneal ligament cells, and engineered skin—currently approved in Spain, highlighting the complexity of regenerating tissues like cardiac muscle.

Stem Cell Therapy: Current Status and Future Prospects

Despite theoretical potential, stem cell applications in tissue repair remain largely in research, with only three treatments—chondrocyte, corneal ligament cells, and engineered skin—currently approved in Spain, highlighting the complexity of regenerating tissues like cardiac muscle.

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What is the current clinical status of stem cell-based therapies, and what are the limitations?

Only three advanced therapy medicinal products are currently approved in Spain: those using chondrocytes, corneal ligament cells, and engineered skin. While research shows promise, widely available, effective treatments are still lacking. Other stem cell applications, such as exosomes, are still under investigation.

nbcnews.com

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Sep 6, 16:19

Spaceflight Accelerates Stem Cell Aging by Ten Times

A new study reveals that stem cells age ten times faster in space than on Earth, highlighting the significant health risks of space travel and offering potential insights into age-related diseases.

Spaceflight Accelerates Stem Cell Aging by Ten Times

A new study reveals that stem cells age ten times faster in space than on Earth, highlighting the significant health risks of space travel and offering potential insights into age-related diseases.

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What are the key findings of the new study on stem cell aging in space?

The study found that stem cells age ten times faster in space than on Earth, exhibiting hallmarks of aging such as increased inflammatory signaling, telomere shortening, and genomic instability. These changes occurred after 32-45 days in microgravity aboard SpaceX spacecraft.

forbes.com

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Aug 23, 01:17

BioRescue Project Offers Hope for Northern White Rhinos

Two remaining northern white rhinos in Kenya are the focus of BioRescue, a project using IVF, stem-cell research, and surrogacy to create viable embryos in an attempt to revive this functionally extinct subspecies.

BioRescue Project Offers Hope for Northern White Rhinos

Two remaining northern white rhinos in Kenya are the focus of BioRescue, a project using IVF, stem-cell research, and surrogacy to create viable embryos in an attempt to revive this functionally extinct subspecies.

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What immediate impact does the successful creation of viable northern white rhino embryos have on the conservation of this critically endangered subspecies?

BioRescue", a global initiative, aims to revive the northern white rhino subspecies through in-vitro fertilization (IVF), stem-cell research, and surrogacy, using eggs from the two remaining females and preserved sperm from deceased males. The project's initial success in creating viable embryos offers a glimmer of hope for this functionally extinct subspecies. This is a crucial step towards restoring the population, although challenges remain.

nos.nl

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Jul 5, 10:10

Lab-Grown Cells Cure Complex Type 1 Diabetes in Clinical Trial

Lab-grown insulin-producing cells successfully cured complex type 1 diabetes in a clinical trial, potentially solving donor shortages and offering a cure for approximately 120,000 patients in the Netherlands, with a new research center in Leiden focusing on broader implementation.

Lab-Grown Cells Cure Complex Type 1 Diabetes in Clinical Trial

Lab-grown insulin-producing cells successfully cured complex type 1 diabetes in a clinical trial, potentially solving donor shortages and offering a cure for approximately 120,000 patients in the Netherlands, with a new research center in Leiden focusing on broader implementation.

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What is the immediate impact of lab-grown insulin-producing cells on treating complex type 1 diabetes, and how many patients could benefit?

A clinical trial shows lab-grown insulin-producing cells can cure complex type 1 diabetes, addressing the donor shortage and offering hope to 120,000 Dutch patients. While most patients manage their blood sugar, this new method offers a potential cure for those with treatment-resistant forms of the disease.

napoli.repubblica.it

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May 20, 19:13

ChemoID Test Significantly Improves Outcomes for Platinum-Resistant Ovarian Cancer

A phase 3 clinical trial published in Nature Partner Journal "Precision Oncology" demonstrates that the ChemoID test, analyzing tumor stem cells to guide chemotherapy selection, significantly improves response rates (50% vs 5%) and progression-free survival (11 months vs 3 months) in patients with p...

ChemoID Test Significantly Improves Outcomes for Platinum-Resistant Ovarian Cancer

A phase 3 clinical trial published in Nature Partner Journal "Precision Oncology" demonstrates that the ChemoID test, analyzing tumor stem cells to guide chemotherapy selection, significantly improves response rates (50% vs 5%) and progression-free survival (11 months vs 3 months) in patients with p...

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What is the immediate impact of the ChemoID test on platinum-resistant ovarian cancer treatment success rates?

A new study published in Nature Partner Journal "Precision Oncology" shows that the ChemoID test, which analyzes tumor stem cells, significantly improves outcomes for patients with platinum-resistant ovarian cancer. The trial showed a 50% response rate in the ChemoID-guided arm versus 5% in the physician-chosen arm.

dailymail.co.uk

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Mar 28, 01:14

Pregnant Woman's Unborn Baby Helps Save Her Life After Car Crash

Kate Via, a 23-year-old pregnant woman from Nebraska, survived a car crash on November 21, 2024, due to her elevated pregnancy blood pressure and her baby's stem cells; she is currently undergoing rehabilitation after waking from a coma.

Pregnant Woman's Unborn Baby Helps Save Her Life After Car Crash

Kate Via, a 23-year-old pregnant woman from Nebraska, survived a car crash on November 21, 2024, due to her elevated pregnancy blood pressure and her baby's stem cells; she is currently undergoing rehabilitation after waking from a coma.

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What are the long-term implications for Via's health and recovery?

Via's case underscores the complex interplay between maternal and fetal physiology in critical medical events. Further research into the protective effects of pregnancy-related factors during trauma could lead to improved medical interventions. Her ongoing recovery serves as a powerful testament to human resilience and the strength of familial support.

es.euronews.com

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Sep 8, 01:15

Space Travel Accelerates Biological Aging: NASA Study

A NASA study, tracking human stem cells across four space missions, reveals that space travel accelerates biological aging, evidenced by reduced capacity of blood cells to produce healthy cells and increased genetic damage.

Space Travel Accelerates Biological Aging: NASA Study

A NASA study, tracking human stem cells across four space missions, reveals that space travel accelerates biological aging, evidenced by reduced capacity of blood cells to produce healthy cells and increased genetic damage.

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What are the key findings of the NASA study regarding the effects of space travel on human cells?

The study found that blood cells sent to space lost their ability to produce new healthy cells and showed increased genetic damage, including DNA damage and shorter telomeres—all signs of accelerated aging. These changes were observed after 32-45 days in space.

tr.euronews.com

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Sep 5, 13:19

Space Travel Accelerates Biological Aging: Study

A new study tracking changes in human stem cells during four space missions reveals that space travel may accelerate biological aging, as evidenced by reduced ability of blood cells to generate new cells and increased genetic damage.

Space Travel Accelerates Biological Aging: Study

A new study tracking changes in human stem cells during four space missions reveals that space travel may accelerate biological aging, as evidenced by reduced ability of blood cells to generate new cells and increased genetic damage.

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What specific biological changes were observed in human stem cells exposed to space?

The study found that hematopoietic stem and progenitor cells (HSPCs), responsible for blood cell production, showed a decreased ability to produce healthy new cells after spending 32-45 days in space. They also exhibited increased DNA damage and shorter telomeres, both indicative of accelerated aging.

dailymail.co.uk

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Jul 29, 07:15

Stem-Cell Treatment Shows Promise for Reversing Hearing Loss

A UK clinical trial is testing a new stem-cell treatment for hearing loss caused by auditory nerve damage, injecting lab-grown stem cells into the inner ear to regenerate damaged nerve cells; the trial, involving 20 profoundly deaf patients, will test the treatment's efficacy in reversing hearing lo...

Stem-Cell Treatment Shows Promise for Reversing Hearing Loss

A UK clinical trial is testing a new stem-cell treatment for hearing loss caused by auditory nerve damage, injecting lab-grown stem cells into the inner ear to regenerate damaged nerve cells; the trial, involving 20 profoundly deaf patients, will test the treatment's efficacy in reversing hearing lo...

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What are the key challenges and potential risks associated with this new stem-cell treatment for hearing loss?

This clinical trial addresses the significant unmet need for treatments targeting auditory nerve damage, a leading cause of hearing loss. The treatment's success in animal trials, demonstrating safety and improved hearing, provides a strong foundation for human trials. If successful, this stem-cell therapy could revolutionize hearing loss treatment.

lexpress.fr

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May 25, 16:11

iPSC-Based Therapies Show Promise in Treating Diabetes and Parkinson's Disease

Recent studies show iPSC-derived cells successfully treated diabetes and Parkinson's disease in small clinical trials, offering hope for regenerative medicine, although challenges in cost and scalability remain.

iPSC-Based Therapies Show Promise in Treating Diabetes and Parkinson's Disease

Recent studies show iPSC-derived cells successfully treated diabetes and Parkinson's disease in small clinical trials, offering hope for regenerative medicine, although challenges in cost and scalability remain.

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What challenges remain in translating iPSC technology from promising research results into widely available therapies?

Three recent studies demonstrate the potential of iPSC-based therapies. A Chinese team successfully treated diabetes by transplanting insulin-producing pancreatic cells derived from chemically induced iPSCs, achieving normalized blood glucose levels. Two other teams treated Parkinson's disease by injecting dopamine-producing neurons derived from iPSCs or embryonic stem cells, resulting in improved motor function in most patients.

foxnews.com

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Apr 30, 13:14

CRISPR-Edited Microglia Show Promise in Reversing Alzheimer's in Mice

UCI scientists have developed a new Alzheimer's treatment using CRISPR gene-edited microglia immune cells to break down amyloid plaques in mice, reversing neurodegeneration; this targeted therapy may help overcome the blood-brain barrier, offering a promising new avenue for Alzheimer's and other neu...

CRISPR-Edited Microglia Show Promise in Reversing Alzheimer's in Mice

UCI scientists have developed a new Alzheimer's treatment using CRISPR gene-edited microglia immune cells to break down amyloid plaques in mice, reversing neurodegeneration; this targeted therapy may help overcome the blood-brain barrier, offering a promising new avenue for Alzheimer's and other neu...

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What is the significance of UCI's new Alzheimer's treatment, and how does it address current challenges in treating the disease?

UCI scientists have developed a new Alzheimer's treatment using CRISPR gene editing to modify microglia immune cells, enabling them to break down amyloid plaques in mice brains, reversing neurodegeneration. This approach uses the brain's own immune system as a targeted drug delivery system, potentially reducing side effects.

dailymail.co.uk

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Mar 25, 01:11

Stem Cell Therapy Shows Promise in Treating Paralysis from Spinal Cord Injuries

Four Japanese men paralyzed by spinal cord injuries showed significant recovery after receiving injections of induced pluripotent stem (iPS) cells; one can now stand and is learning to walk, while another regained some arm and leg movement, demonstrating a potential breakthrough in spinal cord injur...

Stem Cell Therapy Shows Promise in Treating Paralysis from Spinal Cord Injuries

Four Japanese men paralyzed by spinal cord injuries showed significant recovery after receiving injections of induced pluripotent stem (iPS) cells; one can now stand and is learning to walk, while another regained some arm and leg movement, demonstrating a potential breakthrough in spinal cord injur...

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What are the immediate and specific impacts of this stem cell therapy trial on treating paralysis from spinal cord injuries?

A fully paralyzed man in Japan can now stand and is learning to walk after receiving an injection of reprogrammed stem cells, showing significant progress in treating spinal cord injuries. Another participant regained movement in some arm and leg muscles. This breakthrough involved induced pluripotent stem (iPS) cells, demonstrating their potential in repairing damaged spinal cords.

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